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Sensory rhodopsin II : ウィキペディア英語版 | Sensory rhodopsin II
Sensory rhodopsin II (SRII), also known as ''pharaonis'' phoborhodopsin (''p''pR), is a membrane protein of archaea, responsible for generation of phototaxis signal. Sensory rhodopsin II is found in ''Halobacterium salinarum'' and ''Natronomonas pharaonis'' == Structure == Structure of sensory rhodopsin II is typical for microbial rhodopsin. It consists of seven transmembrane a-helices with retinal molecule connected via Schiff base to K205. Notable feature of sensory rhodopsin II is presence of charged residue Y199 on the surface of the hydrophobic region. This residue is responsible for binding of sensory rhodopsin II transducer protein - HtrII. HtrII consists of two transmembrane helices, two HAMP-domains and methyl-accepting signalling domain. In case of ''Halobacterium salinarum'' HtrII also comprises extracellular chemosensor region, which is responsible for serine sensing.
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